Motif ID: STAT5{A,B}.p2

Z-value: 1.223


Transcription factors associated with STAT5{A,B}.p2:

Gene SymbolEntrez IDGene Name
STAT5A 6776 signal transducer and activator of transcription 5A
STAT5B 6777 signal transducer and activator of transcription 5B

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT5Achr17_+_376930900.263.3e-01Click!
STAT5Bchr17_-_376819170.155.7e-01Click!


Activity profile for motif STAT5{A,B}.p2.

activity profile for motif STAT5{A,B}.p2


Sorted Z-values histogram for motif STAT5{A,B}.p2

Sorted Z-values for motif STAT5{A,B}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5{A,B}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_22305570 1.952 NM_005015
 OXA1L
oxidase (cytochrome c) assembly 1-like
chr19_+_49361054 1.891 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
 ZNF226




zinc finger protein 226




chr14_+_23700261 1.692 NM_006084
 IRF9
interferon regulatory factor 9
chr14_-_19951417 1.686 NM_007110
 TEP1
telomerase-associated protein 1
chr6_+_139136349 1.676 NM_015439
 CCDC28A
coiled-coil domain containing 28A
chr19_+_49309350 1.665 NM_013362
 ZNF225
zinc finger protein 225
chr19_-_49552638 1.529 NM_001083335
NM_013380
 ZFP112

zinc finger protein 112 homolog (mouse)

chr19_+_49198916 1.527 NM_006300
 ZNF230
zinc finger protein 230
chr20_-_18425811 1.464 NM_006606
 RBBP9
retinoblastoma binding protein 9
chr17_+_36515166 1.464 NM_001146041
 KRTAP4-9
keratin associated protein 4-9
chr16_-_69030421 1.405 NM_006927
 ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr19_+_49290319 1.405 NM_013398
 ZNF224
zinc finger protein 224
chr2_-_142605010 1.374 LRP1B
low density lipoprotein receptor-related protein 1B
chr9_+_103200939 1.365 NM_003452
NM_197977
 ZNF189

zinc finger protein 189

chr2_+_95194903 1.358 NM_001017396
NM_021088
 ZNF2

zinc finger protein 2

chr19_-_51058177 1.346 NM_004819
 SYMPK
symplekin
chr19_-_49131250 1.310 NM_003425
 ZNF45
zinc finger protein 45
chr19_-_62680703 1.269 NM_001024596
NM_001144068
 ZNF772

zinc finger protein 772

chr2_-_85435074 1.257 NM_017750
 RETSAT
retinol saturase (all-trans-retinol 13,14-reductase)
chr2_+_95195260 1.254 ZNF2
zinc finger protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
1.76 5.44e-03 GO:0006355 regulation of transcription, DNA-dependent
1.71 5.67e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.69 1.84e-02 GO:0051252 regulation of RNA metabolic process
1.66 1.05e-02 GO:0010468 regulation of gene expression
1.66 1.39e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.61 2.41e-02 GO:0031326 regulation of cellular biosynthetic process
1.59 3.50e-02 GO:0009889 regulation of biosynthetic process
1.59 3.58e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.55 1.17e-02 GO:0060255 regulation of macromolecule metabolic process
1.49 4.84e-02 GO:0031323 regulation of cellular metabolic process
1.49 4.96e-02 GO:0080090 regulation of primary metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.49 3.05e-06 GO:0005634 nucleus
1.36 7.73e-08 GO:0043231 intracellular membrane-bounded organelle
1.35 8.71e-08 GO:0043227 membrane-bounded organelle
1.34 2.46e-09 GO:0043229 intracellular organelle
1.34 3.08e-09 GO:0043226 organelle
1.25 1.88e-07 GO:0044424 intracellular part
1.22 2.97e-06 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.90 3.07e-05 GO:0008270 zinc ion binding
1.82 4.62e-05 GO:0046914 transition metal ion binding
1.80 9.26e-05 GO:0003677 DNA binding
1.58 8.17e-04 GO:0003676 nucleic acid binding